Acetyl-l-carnitine

• Recruiting NCT NCT06126315

  Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALS

  Not yet reported, Not yet reported Mario Negri Institute for Pharmacological Research 246 participants Est. completion 2027-09 19 sites Stand-alone
  Other conditions: Amyotrophic Lateral Sclerosis
  View official trial listing →
• Recruiting NCT NCT06247813

  Pilot Study: Impact of Biomarker-Guided Dietary Supplementation on Quality-of-Life Measures in Subjects With Chronic Pain

  Not yet reported Ethos Research & Development 75 participants Est. completion 2025-07-30 1 site Stand-alone
  Other conditions: Chronic Pain
  View official trial listing →
• Completed NCT NCT00050271

  Acetyl-L-Carnitine for the Treatment of NRTI-Associated Peripheral Neuropathy

  Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 27 participants Est. completion 2007-01 11 sites
  Other conditions: HIV Infections, Peripheral Nervous System Diseases
  View official trial listing →
• Status unknown NCT NCT00225160

  ALCAR Prophylaxis Study

  Not yet reported Royal Free Hampstead NHS Trust 50 participants 1 site
  Other conditions: HIV Infections, Distal Symmetric Polyneuropathy
  View official trial listing →
• Completed NCT NCT00393770

  Acetylcarnitine and Insulin Sensitivity

  Not yet reported Mario Negri Institute for Pharmacological Research 43 participants Est. completion 2007-09 1 site
  Type 2 diabetes
  View official trial listing →
• Terminated NCT NCT00555841

  Safety and Efficacy of ALC in Breast Cancer in Subjects With Fatigue

  Not yet reported Sigma-Tau Research, Inc. 27 participants Est. completion 2008-09 1 site
  Other conditions: Breast Cancer
  View official trial listing →
• Completed NCT NCT00572741

  Treating Oxidative Stress and the Metabolic Pathology of Autism

  Not yet reported Arkansas Children's Hospital Research Institute 39 participants Est. completion 2016-04 1 site
  Other conditions: Autistic Disorder
  View official trial listing →
• Completed NCT NCT00581919

  Ph 2 Bortezomib, Dexamethasone, + Doxorubicin With ALCAR for Previously Treated Multiple Myeloma

  Not yet reported University of Wisconsin, Madison 32 participants Est. completion 2013-07 5 sites Stand-alone
  Other conditions: Multiple Myeloma
  View official trial listing →
• Completed NCT NCT00592488

  Acetyl-L-Carnitine in the Treatment of Septic Shock

  Not yet reported, Not yet reported Vanderbilt University 13 participants Est. completion 2009-09 1 site
  Other conditions: Septic Shock
  View official trial listing →
• Completed NCT NCT00719706

  The Use of a Mitochondrial Enhancement Treatment in Bipolar Disorder

  Not yet reported Mclean Hospital 40 participants Est. completion 2011-05 1 site
  Other conditions: Bipolar Depression
  View official trial listing →
• Completed NCT NCT00751205

  Prevention of Sagopilone-induced Neurotoxicity With Acetyl-L-Carnitine (ALC)

  Not yet reported Bayer 150 participants Est. completion 2010-08 22 sites Stand-alone
  Other conditions: Prostate Cancer, Ovarian Cancer
  View official trial listing →
• Completed NCT NCT00775645

  S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, II, or IIIA Breast Cancer Undergoing Chemo

  Not yet reported SWOG Cancer Research Network 437 participants Est. completion 2013-06 295 sites Stand-alone
  Other conditions: Breast Cancer, Chemotherapeutic Agent Toxicity, Fatigue, Neuropathy, Neurotoxicity
  View official trial listing →
• Terminated NCT NCT00903695

  MemoryXL Effects on Mild Cognitive Impairment Patients

  Not yet reported University of Oklahoma 10 participants Est. completion 2011-05 2 sites Stand-alone
  Other conditions: Mild Cognitive Impairment
  View official trial listing →
• Completed NCT NCT00984750

  Acetyl-L-Carnitine in Type 2 Diabetes

  Not yet reported Mario Negri Institute for Pharmacological Research 229 participants Est. completion 2012-12 5 sites Stand-alone
  Other conditions: Diabetes Type 2, Hypertension
  View official trial listing →
• Completed NCT NCT01054768

  Antioxidant Therapy to Reduce Inflammation in Sickle Cell Disease

  Not yet reported UCSF Benioff Children's Hospital Oakland 37 participants Est. completion 2013-04 1 site Stand-alone
  Other conditions: Anemia, Sickle Cell
  View official trial listing →
• Status unknown NCT NCT01075334

  Is a Carnitine Based Food Supplement (PorimoreTM) for Infertile Men Superior to Folate and Zinc With Regard to Pregnancy Rates in Intrauterine Insemination Cycles?

  Not yet reported Shaare Zedek Medical Center 100 participants Est. completion 2012-12 1 site
  Other conditions: Male Infertility
  View official trial listing →
• Completed NCT NCT01223729

  Acetyl-L-Carnitine Reduces Depression and Improves Quality of Life in Patients With Minimal Hepatic Encephalopathy

  Not yet reported University of Catania 67 participants Est. completion 2005-11 1 site Stand-alone
  Other conditions: Minimal Hepatic Encephalopathy
  View official trial listing →
• Completed NCT NCT01223742

  Oral Acetyl-L-Carnitine Therapy Reduces Fatigue In Hepatic Encephalopathy

  Not yet reported University of Catania Est. completion 2006-12 1 site Stand-alone
  Other conditions: Hepatic Encephalopathy
  View official trial listing →
• Completed NCT NCT01223768

  Acetyl-L-Carnitine In Severe Hepatic Encephalopathy

  Not yet reported University of Catania Est. completion 2005-12 1 site Stand-alone
  Other conditions: Hepatic Encephalopathy (Grade 3 of the West Haven Grading Scale)
  View official trial listing →
• Completed NCT NCT01320527

  A Clinical Trial of a Vitamin/Nutriceutical Formulation for Alzheimer's Disease

  Not yet reported University of Massachusetts, Worcester 135 participants Est. completion 2012-04 8 sites Stand-alone
  Other conditions: Alzheimer's Disease, Mild Cognitive Impairment
  View official trial listing →
• Terminated NCT NCT01379976

  Acetyl-L-carnitine in Combination With a Cisplatin-containing Chemotherapy as First Line Treatment of Advanced or Metastatic Non Small Cell Lung Cancer

  Not yet reported Mario Negri Institute for Pharmacological Research 107 participants Est. completion 2014-10 21 sites
  Other conditions: Non Small Cell Lung Cancer
  View official trial listing →
• Completed NCT NCT01381354

  Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)

  Not yet reported University of Iowa 38 participants Est. completion 2016-05 1 site
  Other conditions: Multiple Sclerosis
  View official trial listing →
• Withdrawn NCT NCT01471652

  Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder

  Not yet reported Columbia University Est. completion 2013-02 1 site
  Other conditions: Chronic Fatigue Syndrome
  View official trial listing →
• Withdrawn NCT NCT01492920

  Acetyl-L-Carnitine Hydrochloride in Preventing Peripheral Neuropathy in Patients With Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer Undergoing Chemotherapy

  Not yet reported Gynecologic Oncology Group Stand-alone
  Other conditions: Fatigue, Malignant Ovarian Mixed Epithelial Tumor, Neuropathy, Neurotoxicity Syndrome, Ovarian Brenner Tumor, Ovarian Clear Cell Cystadenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian Mucinous Cystadenocarcinoma, Ovarian Serous Cystadenocarcinoma, Pain, Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Primary Peritoneal Carcinoma
  View official trial listing →
• Completed NCT NCT01515839

  Single Photon Emission Computed Tomography (SPECT) Imaging Study of Professional American Football Players

  Not yet reported Amen Clinics, Inc. 100 participants Est. completion 2010-06 1 site Stand-alone
  Other conditions: Traumatic Brain Injury
  View official trial listing →
• Completed NCT NCT01524861

  Sympathetic Heart Innervation in Patients With Tako-Tsubo Cardiomyopathy

  Not yet reported University of Campania Luigi Vanvitelli 90 participants Est. completion 2016-01 1 site
  Other conditions: Apical Ballooning Syndrome, Nervous System Diseases, Sympathetic
  View official trial listing →
• Completed NCT NCT01526564

  Clinical Study on Acetyl-L-Carnitine

  Not yet reported Lee's Pharmaceutical Limited 239 participants Est. completion 2011-07
  Other conditions: Peripheral Sensory Neuropathy
  View official trial listing →
• Completed NCT NCT01537549

  Alpha-lipoic Acid/L-acetyl Carnitine for Progressive Supranuclear Palsy

  Not yet reported, Not yet reported Weill Medical College of Cornell University 11 participants Est. completion 2015-04-07 1 site
  Other conditions: Progressive Supranuclear Palsy
  View official trial listing →
• Completed NCT NCT01553968

  Effects of Acute Exercise on Acetylcarnitine Concentration in Endurance Trained and Untrained Subjects

  Not yet reported Maastricht University Medical Center 9 participants Est. completion 2014-06 1 site
  Type 2 diabetes
  View official trial listing →
• Completed NCT NCT01695317

  Effect of Acetyl-L-carnitine in Migraine

  Not yet reported Norwegian University of Science and Technology 72 participants Est. completion 2014-09 1 site
  Other conditions: Migraine
  View official trial listing →
• Completed NCT NCT01752868

  Can Fish Oil and Phytochemical Supplements Mimic Anti-Aging Effects of Calorie Restriction?

  Not yet reported Washington University School of Medicine 56 participants Est. completion 2012-08 1 site Stand-alone
  Other conditions: Healthy Volunteers
  View official trial listing →
• Withdrawn NCT NCT01872351

  Therapy for Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder

  Columbia University Est. completion 2012-11 1 site
  Other conditions: Chronic Fatigue Syndrome
  View official trial listing →
• Completed NCT NCT01909557

  Acetyl-L-Carnitine Supplementation During HCV Therapy With Peg IFN-α2b Plus Ribavirin: Effect on Work Performance.

  Not yet reported University of Catania 62 participants Est. completion 2011-12 1 site
  Other conditions: Quality of Life, Daily Activity, Fatigue
  View official trial listing →
• Completed NCT NCT01913964

  Acetyl-L-Carnitine Supplementation During HCV Therapy With Pegylated Interferon-α2b Plus Ribavirin

  Not yet reported University of Catania Est. completion 1997-10 Stand-alone
  Other conditions: Work Productivity and Activity Impairment in Workers With Chronic C Hepatitis, Fatigue in Workers With Chronic C Hepatitis, Fatigue
  View official trial listing →
• Status unknown NCT NCT01921868

  An Open-label Study of the Effects of Acetyl-L-Carnitine on Cardiovascular Outcomes in Friedreich's Ataxia

  Not yet reported University of South Florida 20 participants Est. completion 2017-06 1 site Stand-alone
  Other conditions: Friedreich's Ataxia
  View official trial listing →
• Completed NCT NCT02072759

  Acetylcarnitine and Metabolic Flexibility

  Not yet reported Maastricht University Medical Center 24 participants Est. completion 2016-06 1 site
  Other conditions: Glucose Intolerance
  View official trial listing →
• Completed NCT NCT02141035

  Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome

  Not yet reported, Not yet reported University of Alberta 20 participants Est. completion 2017-09 3 sites Stand-alone
  Other conditions: Carpal Tunnel Syndrome, Compression Neuropathy
  View official trial listing →
• Completed NCT NCT02173132

  Acetyl-L-Carnitine Reduces Perceived Work Stress and Improves Work Ability and Work Performance in Hepatic Encephalopathy

  Not yet reported University of Catania 94 participants 1 site
  Other conditions: Work Stress, Work Ability, Work Performance
  View official trial listing →
• Terminated NCT NCT02538146

  Effect of Acetyl-L-carnitine on Chronic Pancreatitis

  Not yet reported Karin High 3 participants Est. completion 2016-10 1 site Stand-alone
  Other conditions: Chronic Pancreatitis
  View official trial listing →
• Terminated NCT NCT02598622

  A Pilot Study Investigating the Effects of Acetyl-L-Carnitine and Vincristine-Induced Neuropathy in Pediatric Patients With ALL

  Not yet reported Indiana University 8 participants Est. completion 2016-01 Stand-alone
  Other conditions: Vincristine Induced Neuropathy
  View official trial listing →
• Status unknown NCT NCT02696512

  A Study of IBRF Disorders of Consciousness Advanced Care/MultiModal Care Protocol in Severe Disorders of Consciousness

  Not yet reported, Not yet reported International Brain Research Foundation 30 participants Est. completion 2017-04 1 site
  Other conditions: Brain Injury
  View official trial listing →
• Completed NCT NCT02835664

  Nicotinamide Riboside and Metabolic Health

  Not yet reported Maastricht University Medical Center 15 participants Est. completion 2018-12 1 site
  Other conditions: Obesity, Insulin Resistance
  View official trial listing →
• Completed NCT NCT02891512

  Very Low Frequency Magnetic Fields Versus the Supplement "Xinepa" in the Treatment of the Carpal Tunnel Syndrome

  Not yet reported University of Roma La Sapienza 31 participants Est. completion 2016-01 1 site Stand-alone
  Other conditions: Carpal Tunnel Syndrome
  View official trial listing →
• Completed NCT NCT02955706

  Assessment the Efficacy of Acetyl-L-carnitine in Patient With Alzheimer's Disease

  Not yet reported Dong-A ST Co., Ltd. 265 participants Est. completion 2019-01-25 1 site Stand-alone
  Other conditions: Alzheimer Disease
  View official trial listing →
• Completed NCT NCT02971878

  Comparisons of Human Embryonic Development Using Single Medium With and Without the Addition of Antioxidants

  Not yet reported Fertilitetscentrum AB 128 participants Est. completion 2018-02-01 1 site
  Other conditions: Culture Media, Blastocyst, Antioxidants, Embryo, Human
  View official trial listing →
• Completed NCT NCT02999958

  Adding Antioxidants Into Human Sequential Culture Media System

  Not yet reported Vitrolife 128 participants Est. completion 2018-05 2 sites
  Other conditions: Culture Media, Blastocyst, Antioxidants, Embryo, Human, Oxygen
  View official trial listing →
• Status unknown NCT NCT03014882

  Sperm DNA Damage in β-thalassemia Major: Is There a Role for Antioxidants?

  Not yet reported, Not yet reported Ain Shams University 30 participants Est. completion 2017-12 3 sites
  Other conditions: Endocrine Disease, Fertility Decreased Male, DNA Damage
  View official trial listing →
• Completed NCT NCT03697928

  Markers of Carnitine Acetyltransferase (CrAT) Protein Activity and Carnitine Availability

  Maastricht University 13 participants Est. completion 2020-02-01 1 site
  Other conditions: Metabolism and Nutrition Disorder, Metabolic Disturbance
  View official trial listing →
• Status unknown NCT NCT03726450

  Myo-inositol and an Antioxidant Mix for the Treatment of Vietnamese Infertile Men

  Not yet reported Andrology and Fertility Hospital of Hanoi 55 participants Est. completion 2020-03-01 1 site
  Other conditions: Male Infertility
  View official trial listing →
• Completed NCT NCT03965819

  A Study to Investigate the Efficacy of Pain Bloc-R in Healthy Participants With Non-pathological Aches and Discomfort

  Not yet reported LifeSeasons Inc. 27 participants Est. completion 2019-08-09 1 site
  Other conditions: Healthy
  View official trial listing →
• Completed NCT NCT04113889

  Effects of Triple Drug Cocktail Therapy on Metabolic, Endocrine Alterations and Perceived Stress in Patients With Poly Cystic Ovary Syndrome

  Not yet reported Khyber Medical University Peshawar 147 participants Est. completion 2020-01-30 1 site
  Other conditions: PCOS
  View official trial listing →
• Completed NCT NCT04177667

  Body Mass Index and Age Correlate With Antioxidant Supplementation Effects on Sperm Quality

  Not yet reported University of Roma La Sapienza 104 participants Est. completion 2017-11-30
  Other conditions: Male Infertility
  View official trial listing →
• Status unknown NCT NCT04346862

  Evaluation the Effect of Acetyl-L-carnitine in Patients With Mild Cognitive Impairment Accompanied With Chronic Cerebrovascular Disease

  Not yet reported Hanmi Pharmaceutical Company Limited 636 participants Est. completion 2020-06-30 1 site Stand-alone
  Other conditions: Mild Cognitive Impairment
  View official trial listing →
• Status unknown NCT NCT04509258

  Effectiveness of N-acetyl Cysteine, Acetyl L- Carnitine and Medicated Paraffin Oil in Aluminium Phosphide Poisoning

  Not yet reported Cairo University 100 participants Est. completion 2021-12 1 site
  Other conditions: the Study Focus to Improve the Standard of Care Used for Aluminuim Phosphide Poisoning and to Save Patients With the Minimal Organ Damage
  View official trial listing →
• Status unknown NCT NCT04623619

  Efficacy and Safety of Acetyl L-Carnitine in COVID-19 Patients With Mild-to-Moderate Disease

  Not yet reported Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo 100 participants Est. completion 2021-07-31
  Other conditions: Covid19
  View official trial listing →
• Completed NCT NCT04790188

  Effect of a Nootropic on the Cognitive Performance in Young Adults

  Not yet reported Universidad de Granada 25 participants Est. completion 2022-05-15 1 site
  Other conditions: Cognitive Change
  View official trial listing →
• Status unknown NCT NCT05284487

  Clinical Trial to Evaluate Safety and Efficacy of Jalosome® Soothing Gel.

  Not yet reported Welcare Industries SpA 57 participants Est. completion 2024-03 1 site
  Other conditions: Radiation-induced Dermatitis
  View official trial listing →
• Completed NCT NCT05355311

  Enhancing the Effects of Alcohol Treatment With L-Carnitine

  Not yet reported Brown University 24 participants Est. completion 2025-05-31 1 site
  Alcohol use disorder
  View official trial listing →
• Status unknown NCT NCT05601479

  Preventive Effect of Acetyl-L-carnitine on Oxaliplatin-induced Peripheral Neuropathy

  Not yet reported Nanfang Hospital, Southern Medical University 100 participants Est. completion 2024-12-31 1 site Stand-alone
  Other conditions: Acetylcarnitine, Chemotherapy-induced Peripheral Neuropathy
  View official trial listing →
• Completed NCT NCT05616000

  Comparison of Acetyl- L- Carnitine& Folic Acid Versus Coenzyme Q10& Folic Acid on Semen& Hormonal Parameters& Semen Oxidative Status in Patients of Primary Infertility. A Double Blind Randomized Clinical Trial

  Not yet reported Khyber Medical University Peshawar 86 participants Est. completion 2022-11-29 1 site Stand-alone
  Other conditions: Infertility
  View official trial listing →
• Completed NCT NCT05653895

  Independent and Additive Effects Of Micronutrients With Metformin In Patients With PCOS

  Not yet reported Khyber Medical University Peshawar 120 participants Est. completion 2024-02-07 1 site
  Other conditions: PCOS
  View official trial listing →
• Completed NCT NCT05767515

  The Effects of Acetyl-L-Carnitine and Myo/Chiro-Inositol in Patients With PCOS

  Not yet reported Khyber Medical University Peshawar 120 participants Est. completion 2024-03-10 1 site Stand-alone
  Other conditions: Infertility, Female, PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
  View official trial listing →
• Completed NCT NCT06042738

  Investigation of The Effectiveness of Antioxidant Therapy in Oligoasthenoteratozoospermic Infertile Men

  Not yet reported Ondokuz Mayıs University 48 participants Est. completion 2021-11-01 1 site
  Other conditions: Male Infertility
  View official trial listing →
• Completed NCT NCT06078163

  Combined Rehabilitation With ALA, ALC, Resveratrol and Vitamin D in Discogenic Sciatica in Young People

  Not yet reported University of Palermo 130 participants Est. completion 2023-08-22 1 site
  Other conditions: Sciatic Radiculopathy
  View official trial listing →
• Status unknown NCT NCT06122012

  To Evaluate the Efficacy and Safety of HSK16149 With L-carnitine in Diabetic Peripheral Neuralgia Patients in China

  Not yet reported Haisco Pharmaceutical Group Co., Ltd. 136 participants Est. completion 2024-05 1 site
  Other conditions: Diabetic Peripheral Neuropathic Pain
  View official trial listing →
• Active, not recruiting NCT NCT06573229

  LIver FRAilty Management IN Cirrhosis (LIFRAMIN)

  Not yet reported Fondazione Policlinico Universitario Agostino Gemelli IRCCS 30 participants Est. completion 2025-10-30 1 site
  Other conditions: Sarcopenia, Cirrhosis, Liver, Malnutrition; Protein
  View official trial listing →
• Completed NCT NCT07660081

  Effects of Acetyl L-Carnitine Supplementation on Clinical, Metabolic and Inflammatory Symptoms in Obese, Diabetic, Postmenopausal Women With Osteoarthritis

  Not yet reported Khyber Medical University Peshawar 100 participants Est. completion 2026-08-15 1 site Stand-alone
  OsteoarthritisType 2 diabetes Other conditions: Obesity
  View official trial listing →

Not yet reported.

Not yet reported.

• ClinicalTrials.gov — NCT07660081

Also known as: Acetyl-l-carnitine, ALCAR, L-Carnitine

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