#PEMVIDUTIDE Improves Quality of Weight Loss Over #Zepbound
Semaglutide (STEP Trials):
The primary STEP trials for Semaglutide, particularly STEP 1, 2, 3, and 4, typically lasted for about 68 weeks, which is approximately 16 months.
Tirzepatide (SURPASS Trials):
The primary SURPASS trials for Tirzepatide, including SURPASS-1, 2, 3, 4, and 5, generally lasted for around 72 weeks, which is approximately 18 months.
Pemvidutide (MOMENTUM Trials):
At the end of the 48-week trial, subjects receiving Pemvidutide experienced mean weight losses of 10.3%, 11.2%, 15.6% at the 1.2 mg, 1.8 mg, and 2.4 mg doses, respectively, and 2.2% with placebo.
The body composition analysis revealed that 21.9% of the weight loss was lean mass, while 78.1% was fat mass, indicating a higher preservation of lean mass compared to other incretin weight loss drugs where lean mass loss can account for up to 40% of the total weight loss .
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